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Tyrphostin AG1433

Tyrphostin AG1433

CAS: 168835-90-3

Molecular Formula: C16H14N2O2

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Tyrphostin AG1433 - Names and Identifiers

Name Tyrphostin AG1433
Synonyms Tyrphostin AG1433
1,2-Benzenediol, 4-(6,7-dimethyl-2-quinoxalinyl)-
CAS 168835-90-3

Tyrphostin AG1433 - Physico-chemical Properties

Molecular FormulaC16H14N2O2
Molar Mass266.29
In vivo study Chorion allantoic membrane (CAM) assays are used to determine the effects of the Flk-i inhibitors on angiogenesis. Tyrphostin AG1433 (SU1433) is prepared in methylcellulose pellets and applies to the CAMs of 4-6-day-old chicken embryos. Tyrphostin AG1433 prevents the formation of new yessels under the pellets.

Tyrphostin AG1433 - References

biological activity Tyrphostin AG1433 (SU1433) is a tyrosine kinase inhibitor. Tyrphostin AG1433 is also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor with an IC50 of 5.0 μm and 9.3 μm, respectively. Tyrphostin AG1433 prevents angiogenesis.
Cell Line: GB8B cells
Concentration: 0.1 μM, 1 μM, 5 μM, 10 μM, 20 μM, 30 μM, 50 μM, 60 μM, 100 μM
Incubation Time: 72 hours
Result: Induced significant cell death in GB8B cells in a concentration-dependent manner.
Last Update:2024-04-09 21:54:55
Tyrphostin AG1433
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Shanghai Macklin Biochemical Co., Ltd
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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MedChemExpress (MCE)
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Product Name: SU1433; AG1433 Visit Supplier Webpage Request for quotation
CAS: 168835-90-3
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     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: 4-(6,7-Dimethylquinoxalin-2-yl)benzene-1,2-diol Visit Supplier Webpage Request for quotation
CAS: 168835-90-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: 4-(6,7-Dimethylquinoxalin-2-yl)benzene-1,2-diol Request for quotation
CAS: 168835-90-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Tyrphostin AG1433 Visit Supplier Webpage Request for quotation
CAS: 168835-90-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: SU1433; AG1433 Visit Supplier Webpage Request for quotation
CAS: 168835-90-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
View History
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